Amaia Calderón-Larrañaga


Research Associate, Medicine


amaia.calderon.larranaga@ki.se
KI Profile page: http://ki.se/en/people/amacal

Amaia Calderón-Larrañaga
Amaia Calderón-Larrañaga. Photo: Maria Yohuang

Amaia Calderón-Larrañaga, MPH, PhD is currently working as an assistant professor at the Aging Research Center.

Before being recruited at ARC in August 2015 and during her postdoctoral period within the EpiChron Research Group of the Aragon Health Sciences Institute (IACS) in Spain, she has investigated the epidemiology of multimorbidity (e.g. patterns of diseases and geriatric conditions, polypharmacy patterns), and its impact on health systems (e.g. healthcare use, medication adherence, adverse drug events), and patients (e.g. obesity and weight loss, physical activity). She has also been part of the design of a cluster randomized trial in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in the Spanish primary care (Multi-PAP project).

Since her incorporation at ARC, Amaia has initiated an innovative research approach that shifts from the traditional focus on single diseases towards multidimensional and longitudinal health trajectories, using data from the Swedish National Study on Aging and Care (SNAC-K). Thanks to a VR Starting Grant and a Forte Grant (Research on ageing and health) obtained during 2016-2017, she will study the environmental, behavioral and biological determinants of such trajectories, as well as the interaction of these health pathways with the use of medical and social care services needs. The proposed research will allow us to: (a) understand health in old age from a person-centered perspective by considering its complexity and between- and within- individual heterogeneity and (b) provide the evidence needed by healthcare managers to deliver better care at a more appropriate time and place.

Selected publications

  • Calderón A, Vetrano DL, Onder G, Gimeno-Feliu LA, Coscollar-Santaliestra C, Carfí A, Pisciotta MS, Angleman S, Melis RJF, Santoni G, Mangialasche F, Rizzuto D, Welmer AK, Bernabei R, Prados-Torres A, Marengoni A, Fratiglioni L. Assessing and measuring chronic multimorbidity in the older population: a proposal for its operationalization. J Gerontol A Biol Sci Med Sci 2017;72(10):1417-1423.
  • Vetrano DL, Calderón A, Marengoni A, Onder G, Bauer JM, Cesari M, Ferrucci L, Fratiglioni L. An international perspective on chronic multimorbidity: approaching the elephant in the room. J Gerontol A Biol Sci Med Sci 2017 (in press).
  • Santoni G, Marengoni A, Calderón A, Angleman S, Rizzuto D, Welmer AK, Mangialasche F, Orsini N, Fratiglioni L. Defining health trajectories in older adults with five clinical indicators. Gerontol A Biol Sci Med Sci 2017;72(8):1123-1129.
  • Prados A, del Cura I, Prados D, López JA, Leiva F, Calderón A, López F, Gimeno LA, Escortell E, Pico V, Sanz T, Bujalance MJ, Morey M, Boxó JR, Poblador B, Fernández JM, González F, Ramiro MD, Coscollar C, Martín J, Barnestein MP, Valderas JM, Marengoni A, Muth C. Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy: study protocol of a cluster randomized clinical trial (Multi-PAP project). Implement Sci 2017;12(1):54.
  • Haaksma ML, Vilela LR, Marengoni A, Calderón A, Leoutsakos JS, Olde Rikkert MGM, Melis RJF. Comorbidity and progression of late onset Alzheimer’s disease: A systematic review. PLoS One. 2017 May 4;12(5):e0177044.
  • Calderón A, Diaz E, Poblador B, Gimeno LA, Abad JM, Prados A. Non-adherence to antihypertensive medication: the role of mental and physical comorbidity. Int J Cardiol 2016;15;207:310-6. PMID: 26814635.1.
  • Diaz E, Kumar BN, Gimeno LA, Calderón A, Poblador B, Prados A. Multimorbidity among registered immigrants in Norway: the role of reason for migration and length of stay. Trop Med Int Health 2015;20(12):1805-14. PMID: 26426974.
  • Calderón A, Abad JM, Gimeno LA, Marta J, González F, Clerencia M, Poblador B, Poncel A, Prados A. Global health care use by patients with type 2 diabetes: does the type of comorbidity matter? Eur J Intern Med 2015;26(3):203-10.
  • Clerencia M, Calderón A, Martínez N, Vergara I, Aldaz P, Poblador B, Machón M, Egüés N, Abellán G, Prados A. Multimorbidity patterns in hospitalized older patients: associations among chronic diseases and geriatric syndromes. PLoS One 2015;10(7):e0132909. PMID: 26208112.
  • Prados A, Calderón A, Hancco J, Poblador B, van den Akker M. Multimorbidity patterns: a systematic review. J Clin Epidemiol. 2014;67(3):254-66.
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